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LeuceMine™ is rated the #1 dietary sports supplement for recovery by the physicians of PPP. It’s been said again and again that you can’t be serious about results and exclude LeuceMine™ from your supplementation arsenal.
Below you will find a series of “Questions” and “Answers” designed to help you better understand the role of LeuceMine™ in your program.

Q: What is LeuceMine™?

A: LeuceMine™ is a formula that produces a complex yet powerful metabolic effect. Countless strength coaches and elite athletes regard it as the premier pre/post workout supplement on the market. Strength training coaches whose clients are professional and world class athletes are paid a lot of money to maximize their client’s performance capabilities and can give them any supplement they want. They choose LeuceMine™ the #1 choice of elite athletes and coaches alike.

Q: What is in LeuceMine™?

A: The LeuceMine™ formula is comprised of the amino acid L-Glutamine and the 3 Branched Chain Amino Acids (BCAA) L-Leucine, L-Isoleucine, and L-Valine. Ongoing research is directed at further refining the amino acid ratios so as to maximize both its potent anti-catabolic and anabolic effects.

Q: Who should use LeuceMine™?

A: Anyone that is serious about results. Baseball, basketball, football, hockey, soccer, and tennis players as well as bodybuilders, power lifters, and track and field athletes alike all share the common need to blunt the catabolic effects of cortisol, which is induced as a result of resistance training and athletic participation. Everyone should use LeuceMine™. No exceptions!

Q: When should LeuceMine™ be used?

A: There are several strategies for its use. It’s most popular is when it’s stacked with Nitro-E8™ prior to and during training in which case Nitro-E8™ is consumed immediately after training. When used as a stand alone its best to either;

1. Use the entire dosage during training, or
  2.   Increase your typical dosage and split it up between “During” and “Post” workout.

Q: Should LeuceMine™ be cycled?

A: No, because cortisol levels rise at the onset of every training experience and the need to blunt its destructive/catabolic effects are ongoing. Many of today’s dietary supplements like thermogenic formulas must be cycled otherwise, over time, they become less and less effective. The body builds a resistance to its ingredients and it requires more and more to produce the same or a lesser effect. By contrast, LeuceMine™ doesn’t have its effects reduced as a result of extended ongoing use. Ongoing use is not only encouraged but necessary.

Q: Is LeuceMine™ 100% safe and natural?

A: Absolutely. One of the ingredients in the formula is the amino acid L-Glutamine. L-Glutamine is the most abundantly found amino acid in our bodies with 60% residing within skeletal muscle. The remainder of the formula’s principle ingredients is BCAA’s, considered essential amino acids. This means our body must consume these daily from external sources. These ingredients are not only NATURAL and SAFE but also ESSENTIAL to athletes.

Q: Can LeuceMine™ be used everyday?

A: This is a very good question. The answer is at least 5 times a week. Because LeuceMine™ tastes so good athletes tend to use it as a snack. Take the maximum dosage at the right time according to the label. Taking the most when it matters is better than some all the time. Again, refer to the formula on the bottle and stay on the high end of the recommended dosage.

Q: Are there any side effects from using LeuceMine™?

A: No way. It is extremely safe and natural. You can give LeuceMine™ to your kids and rest assured that it is completely and totally safe.

Q: What is the recommended dosage for the use of LeuceMine™?

A: We want everyone to gain the maximum benefit possible from its use. So we asked Dr. Joseph Rossi to provide a range that users could refer to in order to determine dosage. According to Dr. Joseph Rossi those individuals wishing to maximize its protein and glutamine sparing effects should take their bodyweight and deduct their body fat poundage to arrive at what is referred to as LBM or lean body mass. This is done by;

Strategy #1
  1.   Taking the total body weight (let’s say 200 pounds) and deducting the body fat percentage (let’s say 10%). In this case one would deduct 20 pounds (representing 10% of the total body weight) from 200 pounds (total body weight) and arrive at 180 pound (representing LBM).
  2.
  Next, the 180 pounds would be multiplied by .20 (the highest multiple to be used) and arrive at 36 or 36 grams. According to Dr. Rossi one strategy is to take that number and split it into two equal doses, which in this case would be 18 grams. In this case, the dosage represents the optimal grams of LeuceMine™ to be consumed 20 minutes prior to and immediately after training.
  Strategy #2
  Over the years the most popular applied usage and the one endorsed by both Rossi and the physicians of PPP is as follows;
  1.
  Repeat the same calculation method presented above.
  2.
  Instead of splitting up the dosage take it all during the workout.
The second strategy is most popular and the one used in conjunction with Nitro-E8™. Both products should always be used together.

Q: What are some options for mixing LeuceMine™?

A: LeuceMine™ is best mixed with water. It’s not advised that it be mixed in a cup with a spoon because some of the amino acids are not water-soluble. When mixed in a glass, the glutamine will rise to the top and eventually mix. However, when mixed in a shaker it mixes to perfection. In order to get LeuceMine™ to taste perfect I suggest you experiment with how much water and how much LeuceMine™ to be used when mixing. It is further recommended that you avoid mixing LeuceMine™ with fruit juices, however, there have been reports that it mixes wonderfully with either Gatorade or Crystal Light. 800.306.1913

Q: Is LeuceMine™ Sugar Free?

A: Absolutely! This is the second-generation version of LeuceMine™ and it’s absolutely positively sugar free. If MyoTrend as a company had elected to water the product down by adding sugar you find LeuceMine™ priced for considerably less. However, the goal was the creation of a super ultra effective “Elite” formulation for recovery and dilution of any kind in order to improve margins was never a remote consideration.

Q: What are the primary benefits of BCAA and Glutamine - the ingredients comprising LeuceMine™?

A: BCAA provide a precursor of glutamine and are directly up-taken by skeletal muscle. The presence of BCAA in LeuceMine™ provides a threefold effect:

1. The capability of independently stimulating protein synthesis in humans.
  2.   The ability to be converted directly to glutamine within skeletal muscle.
  3.   The ability to function as a precursor to glucose formation after glycogen stores has been depleted

During intense training, the signal for muscle breakdown may be the release of skeletal muscle glutamine. Providing supplemental L-glutamine has been shown in documented clinical studies to attenuate (reduce the degree of effect) this signal. Therefore, the regular use of L-glutamine can have a profound impact on maintaining a positive nitrogen balance, which is essential to muscular development and recovery.

According to Dr. Rossi supplementation with both glutamine and branched-chain amino acids during periods of intense training and muscle stress may preserve better nitrogen balance and hasten recovery during and after weight training.

The amino acid L-Glutamine present in the blood (Glutamine Serum) will attenuate or delay the premature onset of a catabolic environment and provide a protein/muscle sparing effect during training. L-Glutamine will help prevent your muscles from dumping into circulation its stored L-Glutamine which would trigger further muscle wasting during a most critical time. By taking LeuceMine™ during the workout you keep your body from experiencing muscle breakdown prematurely.

Q: How does LeuceMine™ work?

A: The active phase of training is highly catabolic. During this time, glycogen stores are quickly depleted and the liver must synthesized glucose. It performs this function by converting the amino acid L-Alanine to glucose. This amino acid along with L-Glutamine account for more than 50% of the total amino acid released from muscle tissue.

In skeletal muscle, 60% of the free amino acid pool is glutamine. L-Glutamine release is from free glutamine stores within the muscle and from deamination (removal of ammonia molecule) of branched-chain amino acids. This release of skeletal muscle L-Glutamine may be the signal that inhibits protein synthesis in skeletal muscle models during stress.

Providing L-Glutamine and Branched-Chain Amino Acids (BCAA’s) may affect the signal responsible for decreasing protein synthesis. In weight training, the major organ system involved is the skeletal muscles. Repair and re-growth during recovery require amino acids in proportions present in the tissue affected most by the catabolic process. L-Glutamine and Branched-Chain Amino Acids (BCAA’s) in the ratios and dosages such as found in the LeuceMine™ formula are the logical choice.

Simply stated it delays the signal responsible for catabolism and muscle breakdown.

Now, let me put that in layman’s terms. Training is a highly catabolic activity. By just doing the warm up set your body becomes IMMEDIATELY under stress. Under stress your brain (the pituitary gland) sends a signal instructing your body to leech the amino acid L-Glutamine from wherever it can. The first place it will go to is the blood stream and if Glutamine serum levels are below a certain threshold it will next source it from skeletal muscle and then you’re in trouble. You’re in trouble because your muscle will now be volatile and subject to tremendous stress. You will experience muscle wasting throughout the workout and you MUST prevent this.

LeuceMine™ allows you to train in an environment under which muscles are protected and further enhances your performance capabilities through the role of the Branched Chain Amino Acids (BCAA’s) which serve as an alternate fuel source to stressed muscles. BCAA’s will allow you to recover faster and during the workout you will train harder and for longer periods of time with more intensity.

Below Are Additional Questions from Our Readers

LeuceMine™ being taken with Protein and Honey

What is the best way to take LeuceMine™ post workout? Is it OK to take it with whey protein and honey as my post work out drink? I have read that there was a study conducted that suggests honey might be the best post workout source for carbohydrates when added to whey protein. The study was conducted by Dr. Richard Kreider, lead investigator of the study and Director of the Exercise and Sport Nutrition Laboratory at the University of Memphis. This study was presented at the annual National Strength and Conditioning Association meeting. Over on another board the creator of a post work out drink which may be an attempt at replicating LeuceMine™ + whey protein + dextrose + malt dextrin bashed honey as a good post work out carbohydrate.

Yes, honey is a great source of carbohydrates after workouts, but be aware of honey brands and buy good ones. Also, make sure that consumption isn’t within the first 20 minutes post workout as it will hurt your anabolic window. Anyhow, it is a great idea but remember your specific goals and also the amount of honey. You should use about 35 to a maximum of 50 grams combined with 2 scoops of LeuceMine™ and 2 scoops of whey protein. You will have an exceptional post workout drink or meal. Another post workout meal could be sugar free yogurt mixed with whey protein and LeuceMine™ mixed together - excellent and fulfilling. I think Richard is correct up to a point; it depends on your goals, health, events and stress level.

LeuceMine™ and Lack of Soreness

It's impossible for me to get sore while taking LeuceMine™. I know Strength Coaches recommend that everyone take at least 40 grams but I'm a starving student so I usually use between 20 and 30 grams. Regardless, I don't get sore. Why? Times when I have run out or been without it the soreness returns. I mean if I forget to use it even one workout the next day I'm hurting. I'm an information kind of guy and would love to hear about how/why this works.

Every person that has been turned onto LeuceMine™ has had the exact same experience. I remember John Meadows telling me that it took 10 or so days to kick in but when it did, well, like you said...no soreness was the immediate response. I remember John telling me that because he couldn’t get sore it just made him train even harder. In fact, John would do workouts that were so freaking painful just to see if he could get sore.

Heating H2O/Water for LeuceMine™

I have a question that may sound dumb so, please excuse me. I use LeuceMine™ faithfully 30 minutes prior to training. I usually mix it w/ filtered H20 from the fridge. I had an idea of warming the water to a temp of just luke warm in order to see if it dissolved better; sure enough it did. My question is this, does warming the water affect it in any way and can I mix it w/ ribose and creatine at the same time? LeuceMine™ is an awesome product and I highly recommend it to any female or anyone for that matter that wants to get a more intense workouts, as well as, reduce their recovery time and post-workout soreness!

Great question! If you heat the water first without putting LeuceMine™ in the water you’ll be ok. So make sure you heat the water first. The higher temperature increases the rate of absorption secondary to the similarity to body temperature. Yes, you can mix both Ribose and Creatine with LeuceMine™. I’m not the biggest fan of Ribose but Creatine Monohydrate is a definite in the absence of CreaGen™.

How and When to Mix LeuceMine™

I got turned on to LeuceMine™ by our strength coach who told me this would help me recover faster from practice. I take about 40+ grams per workout and the stuff flat-out works. Thanks coach. But my problem is I get water logged. To mix that much LeuceMine™ I use a 1.5-liter water bottle. It has to be this much to taste great. During practice it isn’t a problem but during a regular workout it is tough to get it all in. I need to know how soon before my workout can I start drinking LeuceMine™ so that I don't get that water logged feeling. Also, I'd like to know how much LeuceMine™ John Meadows and Paul Burton take and how they take it.

LeuceMine™ tastes awesome but it’s like any concentrated powder if you mix too much powder with too little water. What I started doing is breaking it up into 2 1-liter doses. Each liter contains 25 g of either orange or grape. I don't know who it was but somebody turned me on to “gronge”, which, of course, is a mixture of grape, and orange. I start sipping my first bottle 30 minutes before I get to the gym and am right when I get there. I'm trained to the point that when I see the gym I have to pee. Once I do I go right to my next bottle, which I'll sip throughout the workout. Remember guys, if your taking Nitro-E8™ post work out don't take LeuceMine™ after you train.

As far as your dosage question I know that John takes about 60 to 70 grams while I take a consistent 50 grams. I have a son “Alex” who as of December 2004 turned 14 and he benches 300 for reps, squats slightly over 300 and leg presses over 1,000 pounds. From last football season to this football season (2005) Alex has added 4 inches in height and 65 pounds in weight. He dominates the line of scrimmage at 252 pounds. What was the intervening factor?

· 9 months of weight training
  ·   The regular usage of Nitro-E8™ (10 tablets after training)
  ·   LeuceMine™ (55 grams during training)
  ·   Regular usage of NitroCene™ a PRD protein powder product used right before bed.

Remember, I give this stuff to my son!

LeuceMine™ and Increased Strength

I just wanted to say something about the product LeuceMine™. I first heard of it from a fellow power lifter who raved about his recuperation from training after using LeuceMine™. I have been using the product for about six weeks and have also noted that I am able to work out heavier and longer while using LeuceMine™. I have noted, in the past, that when I did a personal best lift in a meet such as a squat that my other lifts seemed to be mediocre because I was exhausted from the heavy maximum lift. Last Saturday I participated in a meet and did a personal best squat and bench. My dead lift was also very good with nine out of nine attempts successful. I attribute this to hard training and LeuceMine™. I noticed at the end of the day that I had plenty of energy and strength left over which is very unusual. Most supplements are just a drain on a lifters wallet but, like Creatine, this product really works. I don't have any affiliation with the company or anything either, that's just my personal experience.

Your comments are sincerely appreciated. I can't tell you how rewarding it is to hear feedback telling us that we did a good a job and that our products work. Thank you!

LeuceMine™ and Fat Loss

I recently read an article that discussed a single study showing BCAA's were effective in burning fat, specifically stubborn fat in the abdominal. Please explain how BCAA’s actually do this or should there be more research on this? Just wondering if LeuceMine™ would be effective in your cutting cycles.

This hypothesis is not proven yet but the body thinks it’s breaking down too much tissue so it responds by releasing fat. Also, BCAA’s increase insulin levels so one ends up getting bigger and leaner. Yes, BCCA can cause fat loss but not like you’re thinking.

BCAA's are essential amino acids that provide the body with fuel like sugar. The amino acid L-Leucine elevates insulin levels but because the body hasn't actually consumed sugar the only substance available to go into muscle are amino acids, which build muscle and concurrently increase your metabolic rate, in other words burns fat.

BCAA’s are very effective particularly while engaged in extreme dieting allowing you to hold on to lean mass. LeuceMine™ should be considered an essential component in one’s cutting cycle.

LeuceMine™ and Creatine

I just started using LeuceMine™ for the first time and I love it. Never before have I used a supplement that has worked this good. I have 3 questions that perhaps you can help me with:

1. Can Creatine be mixed with LeuceMine™ and taken at the same time?
  2.   Can LeuceMine™ be mixed with water in the morning and used later - in the early evening without it losing any potency?
  3.   The GNC where I bought my LeuceMine™ was telling me that they’re also bringing in a product called Nitro-E8™. Is Nitro-E8™ something I can take with LeuceMine™?

I’ll try to answer your questions one by one and also give you some helpful hints:

1. Yes you can use creatine and LeuceMine™ together without any problems, and I actually recommend it. But I do need to caution you about the fact that together you experience a relatively quick increase in weight which may or may not be desirable.
  2.   Yes, once mixed, LeuceMine™ must be consumed within 24 hours. After that glutamine changes slowly secondary to a benign chemical reaction with water. Frankly, I would prefer that you put the powder in the empty bottle and mix with water later at the gym rather than have the product mixed all day.
  3.   Combining Nitro-E8™ with LeuceMine™ will give you great results. The key is timing: When you use LeuceMine™ before workouts you provide a form of energy for muscle without sugars and without elevating your insulin levels. The body is provided with the most important amino acids for the prevention of catabolism and the building blocks for muscle in this case nitrogen in the form of Glutamine. After the workout blood amino acids levels are low and your body desperately needs a quick and highly anabolic source of amino acids. This is the time the body needs all the amino acids necessary for building muscle and that is exactly when Nitro-E8™ should be ingested. Why? Because of Nitro-E8™ ability to quickly deliver nitrogen to muscle cells and into your blood stream.